Figure 4. Surgical effects of different treatments in the rat corneal alkali burn model. A, B: Control group (A). Four weeks after transplantation, corneal epithelial defect size > 1/2 quadrant and neovascularization grew rapidly and involved 1/2 quadrants, with ulcer emerged (arrow) (B). The new blood vessels grew into the whole cornea with extremely severe opacity ten weeks after transplantation. C, D: AM group (C). Moderate to severe corneal opacity four weeks after transplantation (D). Corneal neovascularization grew into nearly 3/4 quadrants ten weeks after transplantation. E, F: Non-induced MSC group (E). Moderate corneal opacity with local stromal scar was seen four weeks after surgery (F). Conjunctivalization with apparent neovascularization was found in 1/2–2/3 quadrant ten weeks after surgery. G, H: Induced MSC group (G). The corneal opacity was mild and there were no signs of conjunctival epithelium growing into the cornea four weeks after transplantation (H). Cornea kept transparent and the neovascularization was within 2 mm from limbal ten weeks after surgery.