Table 4 of Ganguly, Mol Vis 2010; 16:1292-1303.


Table 4. Top 10 Molecules with highest and lowest fold change in expression between RB tumor and normal retina: molecules highlighted in bold contain the consensus sequence, M00050, in the 5-kb upstream region of the respective promoter for binding to E2F family of transcription factors.

Upregulated genes Down regulated genes
NUF2 25.229 PDGFRA −61.726
PBK 23.8 TYRP1 −44.016
CCNE2 22.077 ABCA8 −39.006
TOP2A 22.031 SCARA5 −34.263
C8ORF46 21.409 EGFL6 −28.929
SALL1 20.017 ENPP2 −28.538
RRM2 19.616 SYNPO2 −22.238
E2F7 19.11 CLIC5 −21.56
ASPM 18.545 GULP1 −20.645
CDCA7 16.478 PPAP2B −19.521