Molecular Vision: Tang, Mol Vis 2010; 16:113-121. Table 2

Table 2. Gene expression changes greater than 1.8 in the lenses of 10-day-old C57BL/6J mice relative to expression in 129SvJae, in both WT and α3Cx46 KO mice.

Gene	Encoded protein	GenBank accession	Ratio (C57/129)
Gene	Encoded protein	GenBank accession	α3Cx46 WT	α3Cx46 KO
Growth regulation
Gas5	growth arrest specific 5	AI849615	17.1	13.5
Myd116	protein phosphatase 1, regulatory subunit 15A	X51829	3.4*	2.5
Alox15	arachidonate 15-lipoxygenase	L34570	2.4	2.9
erdr1	erythroid differentiation regulator 1	AJ007909	2.5	3.6
Tsc2	tuberous sclerosis 2	U39818	2.3	1.9
SASH1	SAM and SH3 domain-containing 1	AI837786	2.3	2.5
Eif2s2	eukaryotic translation initiation factor 2	AW125491	−1.9	−1.9
ZDHHC5	zinc finger, DHHC domain-containing 5	AI853561	−3	−2†
ZFP728	zinc Finger protein 728	AI152353	2.5	3.2
Dbi	diazepam binding inhibitor	X61431	−2.5*	−2.1
Intracellular Trafficking
Trappc5	trafficking protein particle complex 5	AW120965	5.3	3
Arl10c	ADP-ribosylation factor-like 10C	AA822412	5.9	1.6*
Tbc1d15	TBC1 domain family, member 15	AI19433	2.4	5.3
Tom1	target of myb1 homolog (chicken)	AJ006972	1.9	2†
Metabolism and catabolism
Mod1	malic enzyme, supernatant	J02652	2.4	1.8
Atp7a	ATPase, Cu++ transporting, α polypeptide	U03434	2.4	1.2†
HGSNAT	Heparan-alpha-glucosaminide N-acetyltransferase	AW125274	1.9	2.5
Uble1a	ubiquitin-like 1 activating enzyme E1A	AB024303	−1.6*	−1.9
Ctsl	cathepsin L	X06086	−1.8	−1.9
Car2	carbonic anhydrase 2	M25944	−1.9	−1.8
Gad1	L-glutamate decarboxylase	M55253	−2.2	−2.4
Bckdhb	branched chain ketoacid dehydrogenase E1,beta polypeptide	L16992	−2.7	−3.9
Cytoskeleton
Epb4.1l4a	erythrocyte protein band 4.1-like 4a	D28818	2.5	2.6
Tpm4	tropomyosin 4	AI835858	−3.7	−3
Cell signaling
Pkig	protein kinase inhibitor-γ	U97170	2.1	1.4*
Gnb1	guanine nucleotide binding protein, beta 1	U29055	−1.9	−1.9
F2r	coagulation factor II (thrombin) receptor	AW123850	−2	−1.9
Uhmk1	U2AF homology motif (UHM) kinase 1	AI846236	−2.4	−1.5†
Transcription factor
Gatad2a	GATA zinc finger domain containing 2A	AI840824	2.7	2.2
Ctbp2	C-terminal binding protein 2	AW120820	1.8†	1.9
Miscellaneous
Col6a3	procollagen VI- α3	AF064749	5.5	3.9
Rsad2	viperin	AA204579	6.5	5.1
Fv4	Friend virus susceptibility 4	C78850	4.9	8.9
Rbp1	retinol binding protein 1	X60367	3.5	2.9
Hfe	hemochromatosis	Y12650	2.9	2.7
Snhg6	small nucleolar RNA host gene 6	AA874329	2.6	4.4
Sf3b5	splicing factor 3b, subunit 5	AW047746	1.9	1.4†
Cdv3	carnitine deficiency-associated gene	AI837005	−1.7	−1.8
Kctd12	potassium channel tetramerisation domain 2	AI842065	−2.1	−1.5†
Xist	inactive X specific transcripts	L04961	−3	1.4
Hebp1	heme binding protein 1	AB013095	−7.2	−6.7
Unknown
BC056474	cDNA sequence BC056474	AI853136	3.6	2.3
6720463E02Rik	RIKEN cDNA 6720463E02 gene	AI836322	3.5†	2.4
1810058I24Rik	RIKEN cDNA 1810058I24 gene	AI194274	−2.5	−2.5
2510049I19Rik	RIKEN cDNA 2510049I19 gene	AW258842	−4.8	−6.7
1810037I17Rik	RIKEN cDNA 1810037I17 gene	AW047207	−7	−6.1