Table 3 of Polisetti, Mol Vis 2010; 16:1227-1240. Table 3 of Polisetti, Mol Vis 2010; 16:1227-1240.
Table 3. Differential gene expression between LEC and MC-L in growth factors and cytokine related genes.
Gene |
LEC versus MC-L |
LEC versus MSCBM |
MC-L versus MSCBM |
|---|---|---|---|
| amphiregulin (schwannoma-derived growth factor) (AREG) | 167.6 (Down) | 131.25 (down) | 3.74 (down) |
| transforming growth factor, alpha (TGFA) | 57.21 (down) | 28.49 (down) | |
| fibroblast growth factor binding protein 1 (FGFBP1) | 38.75 (down) | 23.011 (down) | |
| fms-related tyrosine kinase 1 (vascular endothelial growth factor/vascular permeability factor receptor) (FLT1) | 31.0 (up) | 96.42 (down) | |
| Platelet derived growth factor receptor alpha (PDGFRA) | 26.10 (up) | 33.93 (up) | |
| platelet-derived growth factor receptor, beta polypeptide (PDGFRB) | 20.52 (up) | 21.90 (up) | |
| insulin-like growth factor binding protein 5 (IGFBP5) | 17.65 (up) | 14.81 (up) | |
| growth factor receptor-bound protein 14 (GRB14) | 17.23 (down) | 5.82 (down) | 2.95 (down) |
| fibroblast growth factor 2 (basic) (FGF2) | 13.78 (up) | ||
| fibroblast growth factor 11 (FGF11) | 12.83 (down) | ||
| keratinocyte growth factor-like protein 1 (KGFLP1) | 10.9 (up) | 9.85 (up) | |
| fibroblast growth factor receptor 1 (fms-related tyrosine kinase 2, Pfeiffer syndrome) (FGFR1) | 10.50 (up) | 8.96 (up) | |
| insulin-like growth factor 2 (somatomedin A) (IGF2) | 9.9 (up) | 6.2 (up) | |
| connective tissue growth factor (CTGF) | 9.77 (up) | 15.45 (up) | 2.3 (up) |
| pleiotrophin (heparin binding growth factor 8, neurite growth-promoting factor 1) (PTN) | 8.54 (up) | 9.9 (up) | |
| insulin-like growth factor 2 mRNA binding protein 1 (IGF2BP1) | 8.10 (up) | ||
| fibroblast growth factor 1 (acidic) (FGF1) | 8.03 (up) | 5.41 (up) | 7.41 (down) |
| Insulin-like growth factor binding protein 4 (IGFBP4) | 7.65 (up) | 14.2 (up) | 2.96 (up) |
| fibroblast growth factor 7 (keratinocyte growth factor) (FGF7) | 7.51 (up) | 15 (up) | 4.51 (up) |
| platelet derived growth factor D (PDGFD) | 5.97 (up) | 12.7 (up) | |
| fibroblast growth factor binding protein 3 (FGFBP3) | 5.68 (up) | 4.4 (up) | |
| insulin-like growth factor binding protein 5 (IGFBP5) | 5.61 (up) | 5.4 (up) | 2.95 (down) |
| fibroblast growth factor receptor 2 (fgfr2) | 4.50 (down) | 4.89 (up) | |
| Hepatocyte growth factor precursor (Scatter factor) (SF) (Hepatopoeitin-A) | 4.05 (up) | 10.06 (up) | |
| transforming growth factor beta 1 induced transcript 1 (TGFB1I1), transcript variant 2 | 3.94 (up) | 2.97 (up) | |
| nerve growth factor, beta polypeptide (NGFB) | 3.83 (up) | 2.6 (down) | |
| chemokine (C-X-C motif) ligand 2 (CXCL2) | 79.06 (down) | 4.5 (down) | |
| chemokine (C-X-C motif) ligand 3 (CXCL3) | 26.25 (down) | 16.0 (down) | 3.88 (up) |
| chemokine (C-X-C motif) ligand 1 (CXCL1) | 65.87 (down) | 64.9 (down) | |
| chemokine (C-X-C motif) ligand 11 (CXCL11) | 58.344 (down) | 14.42 (down) | |
| chemokine (C-X-C motif) ligand 10 (CXCL10) | 7.71 (down) | 6.97 (down) | |
| chemokine (C-X-C motif) ligand 12 (stromal cell-derived factor 1) (CXCL12) | 34.26 (up) | 82.68 (up) | |
| chemokine (C-C motif) ligand 26 (CCL26) | 11.4 (up) | 2.49 (up) | |
| chemokine (C-C motif) ligand 2 (CCL2) | 23.43 (up) | 3.48 (down) | |
| chemokine (C-C motif) ligand 13 (CCL13) | 12.42 (up) | 2.34 (up) | |
| interleukin 1, alpha (IL1A) | 78.72 (down) | 63.61 (down) | |
| interleukin 1, beta (IL1B) | 48.57 (down) | 28.89 (down) | |
| interleukin 1 receptor, type II (IL1R2) | 12.17 (down) | 21.03 (down) | 3.92 (up) |
| interleukin 1 receptor antagonist (IL1RN) | 20.06 (down) | 15.10 (down) | |
| interleukin 20 receptor, alpha (IL20RA) | 210.69 (down) | ||
| interleukin 18 (interferon-gamma-inducing factor) (IL18) | 78.26 (down) | 56.72 (down) | |
| interleukin 23, alpha subunit p19 (IL23A) | 28.40 (down) | 29.29 (down) | |
| interleukin 11 receptor, alpha (IL11RA) | 15.58 (up) | ||
| neurotrophin 5 (NTF5) | 14.96 (down) | 11.64 (up) | |
| neurotrophin 3 (NTF3) | 16.40 (up) | 7.50 (up) | 7.48 (down) |
| nerve growth factor, beta polypeptide (NGFB) | 3.8 (up) | ||
| Glial cell line-derived neurotrophic factor precursor (Astrocyte- derived trophic factor 1) | 4.24 (up) | 6.56 (up) | |
| GDNF family receptor alpha 1 (GFRA1) | 6.5 (up) | 6.28 (up) | |
| brain-derived neurotrophic factor (BDNF) | 9.15 (up) | 3.69 (up) | 8.68 (down) |