Table 2 of
Polisetti, Mol Vis 2010; 16:1227-1240. Table 2 of
Polisetti, Mol Vis 2010; 16:1227-1240.
Table 2. The differential gene expression between LEC, MC-L and MSC-BM, as measured by the fold change difference of the corresponding genes (Ribosomal genes excluded). Abbreviations: LEC – limbal epithelial cells, MC-L – mesenchymal like cells of limbus, MSC-BM – mesenchymal stem cells of bone marrow.
| Genes differentially expressed in LEC (25 fold overexpression in LEC compared MC-L and MSC-BM) |
|---|
| Keratin 12, T-cell differentiation protein 2 (MAL2), Nebulette, v-myc myelocytomatosis viral related oncogene, ets homologous factor, calbindin 1, Kringle containing transmembrane protein 2, glucosaaminyl (N-acetyl) transferase 2, carcinoembryonic antigen-related cell adhesion molecule 6, Apolipoprotein B mRNA editing enzyme catalytic polypeptide –like 3a, tumor associated calcium signal transducer 1, sciellin, serine peptidase inhibitor kazal type 5, carcinoembryonic antigen-related cell adhesion molecule 1, interleukin 1 alpha, interleukin 18, dual adaptor of phosphotyrosine and 3-phosphoinositides (DAPP1), Transmembrane channel-like 5, claudin 1, defensin beta 1, WAP four-disulfide core domain 5, chemokine (C-X-C motif) ligand 1, dystonin, desmocollin 2, cadherin 1, transforming growth factor alpha, S100 calcium binding protein A8, Serpin peptidase inhibitor clade B member 5, visinin-like 1, interleukin 1 beta, desmoglein 3, matrix metallopeptidase 10, tumor protein p73-like (p63), homeoboxdomain-only protein (HOP), amphiregulin. |
| Genes differentially expressed in MC-L (15 fold overexpression in MC-L compared to LEC and MSC-BM) |
| Vascular endothelial growth factor receptor 1, cadherin 6, forkhead box F1, glutamate receptor ionotrophic, collectin sub-family member 12, SHC (Src homology 2 domain containing) transforming protein 3 (SHC3), AF052115, BC073929. |
| Genes differentially expressed in MSC-BM (20 fold overexpression in MSC-BM compared to LEC and MC-L) |
| growth differentiation factor 6 (GDF6), Urea transporter, erythrocyte (SLC14A1), neurotrophic tyrosine kinase, receptor, type 2 (NTRK2), early growth response 2 (Kro × −20 homolog, Drosophila) (EGR2), secreted phosphoprotein 1 (osteopontin, bone sialoprotein I, early T-lymphocyte activation 1) (SPP1), myogenic factor 6 (herculin) (MYF6), collagen, type XI, alpha 1 (COL11A1), olfactomedin 4 (OLFM4), hepatitis A virus cellular receptor 2 (HAVCR2), homeo box A11, antisense (HOXA11S) on chromosome 7, homeobox C9 (HOXC9), HELAD1S mRNA for helicase, phosphodiesterase 1C, calmodulin-dependent 70 kDa, opioid binding protein/cell adhesion molecule-like (OPCML), transcript variant 2, zinc finger, matrin type 4 (ZMAT4), |
| Genes differentially expressed in limbal explant culture derived cells (LEC and MC-L) over bone marrow (10 fold difference) |
| semaphorin 3D (SEMA3D), matrix metallopeptidase 1 (interstitial collagenase) (MMP1), vitrin (VIT), Lysophosphatidic acid receptor Edg-7 (LPA receptor 3) (LPA-3), keratin 18 (KRT18), transcript variant 1, insulin-like growth factor 2 mRNA binding protein 3 (IGF2BP3), myelin basic protein (MBP), contactin 3 (plasmacytoma associated) (CNTN3), |
| Genes differentially expressed in MC-L, MSC-BM over epithelial cells (over 20 fold difference) |
| nucleosome assembly protein 1-like 3 (NAP1L3), thymocyte selection-associated high mobility group box (TOX), axin 2 (conductin, axil) (AXIN2), phosphodiesterase 11A (PDE11A), potassium voltage-gated channel, Isk-related family, member 4 (KCNE4), dermatan sulfate epimerase-like (DSEL), chemokine (C-X-C motif) ligand 12 (stromal cell-derived factor 1), G protein-coupled receptor 124 (GPR124), protocadherin 18 (PCDH18), hyaluronan and proteoglycan link protein 1 (HAPLN1), collagen, type V, alpha 2 (COL5A2), alpha-2-macroglobulin (A2M), decorin (DCN), cerebellar degeneration-related protein 1, 34 kDa (CDR1), ependymin related protein 1 (zebrafish) (EPDR1), formin 2 (FMN2), Platelete derived growth factor receptor alpha, frizzled homolog 7, dapper, antagonist of beta-catenin, homolog 3, microfibrillar associated protein 5, lysyl oxidase, integrin, alpha 8, junctional adhesion molecule 2, protein kinase C, alpha, platelet-derived growth factor receptor, beta polypeptide. |