Figure 6 of Tanaka, Mol Vis 2010; 16:1194-1205.


Figure 6. Expression patterns of transforming growth factor β-receptor type I and type II in an injured lens epithelium. At day 5 post-injury, multilayered lens epithelial cells in an injured lens were markedly labeled with anti-TGFβ-RI in a wild type (WT; A) mouse, while its immunoreactivity was quite faint in the cells of a tenascin C null (KO; B) mouse. At day 10, the cells of the mutilayer beneath the anterior lens capsule were labeled for TGFβ-RI in both the WT and KO mice (C, D). At day 5 post-injury, the multilayered lens epithelial cells in an injured lens were markedly labeled with anti-TGFβ-RII in a WT mouse (E), while its immunoreactivity was quite faint in the cells of a KO mouse (F). Even at day 10, immunoreactivity for TGFβ-RII was more prominent in the WT cells than in the KO cells (G, H); Bar, 10 μm.