Figure 3. Expression pattern of α-smooth muscle actin (αSMA) in lens epithelial cells of injured lenses. The multicellular layer of epithelial cells at the edge of the broken capsule was strongly labeled with anti-αSMA antibody in a wild-type mouse at days 5 (A, asterisk) and 10 (C, asterisk). On the other hand, in a tenascin-C null (KO) mouse almost none of the epithelial cells in the multicellular layer were stained for αSMA at day 5 (B). At day 10, the majority of the cells were labeled in the KO mouse (D, asterisk). Arrows, edges of the injured anterior capsule. AC, anterior capsule; Bar, 10 μm.