Figure 5. GRP78 and myocilin (MYOC) were expressed in both NTM and GTM cells, and exhibited a diffused distribution throughout the cytoplasm in NTM cells. The expression pattern of GRP78 and MYOC was most overlapping in GTM and treated NTM cells. Perinuclear aggregation of GRP78 expression was observed in GTM and treated NTM cells (white arrow). The Tm slightly upregulated GRP78 expression and STS down-regulated it, while the expression of MYOC did not show much difference. Scale bar=10 μm.