Figure 3 of Reilly, Mol Vis 2010; 16:1041-1046.


Figure 3. Measurement of lens shape. The radial dimension of the lens was measured from the intersection of the optical axis and the equatorial plane as a function of the angle measured from the anterior pole to the posterior pole for wild type, 6-day-old (black solid line); wild type, 3 months (red solid line); wild type, 4 months (blue solid line); heterozygous mutant αA-R49C, 6-day-old (black dashed line); heterozygous mutant αA-R49C, 2.5 weeks (red dashed line); heterozygous mutant αA-R49C, 3 months (blue dashed line); heterozygous mutant αA-R49C, 4 months (green dashed line); homozygous mutant αA-R49C, 6-day-old (black dotted line); homozygous mutant αA-R49C, 2 weeks (red dotted line); homozygous mutant αA-R49C, 4 months (blue dotted line). Note that wild type and αA-R49C heterozygous mutant lenses were nearly spherical with radial distances increasing slightly at the equator (angle=90°), whereas homozygous mutant lenses had a smaller anterior segment and an enlarged posterior segment.