Figure 3. Antiretinal autoantibodies. A: Control serum from 12 subjects was applied to human retinal proteins separated by sodium dodecyl sulfate PAGE. Nonspecific banding patterns were detected. B: Serum from 12 autosomal dominant neovascular inflammatory vitreoretinopathy patients was applied to similar retinal blots, and no specific bands or unique patterns were detected. The major band in all samples indicates cross-reaction of secondary antibody with endogenous human immunoglobulin G (IgG) chains.