Table 1 of Ogando, Mol Vis 2010; 16:1004-1018. Table 1 of Ogando, Mol Vis 2010; 16:1004-1018.
Table 1. GO term analysis of differentially expressed genes between the C and B6a strains at 4 and 8 months-of-age.
GOID |
GO Name |
Number changed |
Percent changed |
Z score |
Permute P statistic |
| GO terms increased in C versus B6a at 4 months | |||||
|---|---|---|---|---|---|
| 16628 | oxidoreductase activity\, acting on the CH-CH group of donors\, NAD or NADP as acceptor | 5 | 55.6 | 4.8 | <0.001 |
| 30054 | cell junction | 25 | 21.9 | 4.746 | <0.001 |
| 8305 | integrin complex | 7 | 41.2 | 4.6 | <0.001 |
| 4716 | receptor signaling protein tyrosine kinase activity | 5 | 57.1 | 4.4 | <0.001 |
| 44420 | extracellular matrix part | 15 | 21.7 | 3.6 | <0.001 |
| 16769 | transferase activity\, transferring nitrogenous groups | 8 | 33.3 | 4.1 | 0.001 |
| 45111 | intermediate filament cytoskeleton | 11 | 26.8 | 3.9 | 0.001 |
| 6958 | complement activation\, classical pathway | 5 | 38.5 | 3.7 | 0.001 |
| 42060 | wound healing | 13 | 22.8 | 3.6 | 0.003 |
| GO terms increased in B6a versus C at 4 months | |||||
| 42401 | biogenic amine biosynthetic process | 6 | 35.3 | 4.4 | <0.001 |
| 299 | integral to membrane of membrane fraction | 4 | 44.4 | 4.3 | 0.001 |
| 42398 | amino acid derivative biosynthetic process | 6 | 27.3 | 3.6 | 0.003 |
| 7222 | Wnt receptor signaling pathway | 4 | 40.0 | 4.0 | 0.004 |
| 46916 | transition metal ion homeostasis | 7 | 23.3 | 3.4 | 0.006 |
| 19886 | antigen processing and presentation of exogenous peptide antigen via MHC class II | 4 | 30.8 | 3.2 | 0.006 |
| 1664 | G-protein-coupled receptor binding | 8 | 20.51282 | 3.147 | 0.007 |
| 8009 | chemokine activity | 6 | 25.0 | 3.3 | 0.009 |
| GO terms increased in C versus B6a at 8 months | |||||
| 3924 | GTPase activity | 26 | 19.0 | 3.3 | <0.001 |
| 6898 | receptor-mediated endocytosis | 8 | 32.0 | 3.6 | 0.001 |
| 5606 | laminin-1 complex | 4 | 57.1 | 4.1 | 0.002 |
| 5740 | mitochondrial envelope | 40 | 16.4 | 3.1 | 0.002 |
| 19752 | carboxylic acid metabolic process | 54 | 15.2 | 3.1 | 0.002 |
| 30865 | cortical cytoskeleton organization and biogenesis | 5 | 41.7 | 3.6 | 0.007 |
| 6778 | porphyrin metabolic process | 6 | 35.3 | 3.4 | 0.009 |
| 87 | M phase of mitotic cell cycle | 23 | 16.5 | 3.4 | 0.009 |
| GO terms increased in B6a versus C at 8 months | |||||
| 50880 | regulation of blood vessel size | 8 | 36.4 | 5.2 | 0 |
| 5720 | nuclear heterochromatin | 6 | 30.0 | 3.9 | 0.001 |
| 10038 | response to metal ion | 4 | 44.4 | 4.3 | 0.004 |
| 8083 | Growth factor activity | 12 | 14.0 | 3.1 | 0.004 |
| 19216 | regulation of lipid metabolic process | 5 | 26.3 | 3.2 | 0.007 |
| 1664 | G-protein-coupled receptor binding | 8 | 20.5 | 3.1 | 0.007 |
| 42773 | ATP synthesis coupled electron transport | 5 | 26.3 | 3.2 | 0.009 |