Figure 2. Amino acid sequence analysis of
2M6 antigen and TopAP protein. Mass spectroscopy analyses
identified 20 unique peptides, each of which align with the TopAP
polypeptide sequence (NCBI accession number gi|642486) with 95%
probability. The TopAP polypeptide sequence is shown, with
the regions of identity to 2M6 peptides underlined. These regions
account for 186 of the 359 amino acids, which is 52% coverage of the TopAP
sequence. The transmembrane region, located at the carboxy terminus of
the polypeptide sequence, is highlighted in gray.