Table 4 of Lu, Mol Vis 2010; 16:1-6. Table 4 of Lu, Mol Vis 2010; 16:1-6.
Table 4. SERPING1 haplotype association with AMD in the Han Chinese subject group.
| Type of AMD |
Haplotype |
Frequency |
Haplotype association (p value) |
Bufferoni correction (p value) |
Odds ratio (95% CI) |
|
|---|---|---|---|---|---|---|
| Case | Control | |||||
| All AMD | H1:CATGTG | 0.63 | 0.57 | 0.0609 | ||
| H2:CGTGTG | 0.04 | 0.06 | 0.1091 | |||
| H3:TGTGCG | 0.06 | 0.02 | 0.0064 | 0.0900 | ||
| H4:TGTACG | 0.03 | 0.04 | 0.3301 | |||
| H5:CGTGCA | 0.04 | 0.03 | 0.2641 | |||
| H6:CGTGCG | 0.02 | 0.05 | 0.0102 | 0.1428 | ||
| H7:CATGTA | 0.02 | 0.03 | 0.4105 | |||
| H8:CATATG | 0.02 | 0.03 | 0.5689 | |||
| H9:TATGTG | 0.02 | 0.01 | 0.3679 | |||
| H10:CGCGCA | 0.02 | 0.01 | 0.5900 | |||
| H11:CGTACA | 0.03 | 0.00 | 0.0008 | 0.0112 | ||
| H12:CGTACG | 0.01 | 0.02 | 0.4070 | |||
| H13:CGTGTA | 0.01 | 0.02 | 0.0628 | |||
| H14:CGCGCG | 0.00 | 0.02 | 0.0060 | 0.0840 | ||
| Wet AMD | H1:CATGTG | 0.63 | 0.57 | 0.0717 | ||
| H2:CGTGTG | 0.03 | 0.06 | 0.0946 | |||
| H3:TGTACG | 0.04 | 0.04 | 0.7668 | |||
| H4:TGTGCG | 0.06 | 0.02 | 0.0042 | 0.0630 | ||
| H5:CGTGCG | 0.02 | 0.05 | 0.0620 | |||
| H6:CATGTA | 0.03 | 0.03 | 0.6366 | |||
| H7:CGTGCA | 0.02 | 0.03 | 0.5447 | |||
| H8:CATATG | 0.02 | 0.03 | 0.2741 | |||
| H9:CGCGCA | 0.02 | 0.01 | 0.5848 | |||
| H10:TATGTG | 0.02 | 0.01 | 0.3616 | |||
| H11:CGTACG | 0.01 | 0.02 | 0.6028 | |||
| H12:CGCGCG | 0.00 | 0.02 | 0.0256 | 0.3840 | ||
| H13:CGTACA | 0.03 | 0.00 | 0.0003 | 0.0045 | ||
| H14:CATGCG | 0.01 | 0.01 | 0.3513 | |||
| H15:CGTGTA | 0.00 | 0.02 | 0.0263 | 0.3950 | ||
| Drusen AMD | H1:CATGTG | 0.62 | 0.57 | 0.2702 | ||
| H2:CGTGTG | 0.04 | 0.06 | 0.5894 | |||
| H3:CGTGCA | 0.11 | 0.03 | 7.87E-05 | 1.10E-03 | 3.72 (1.83–7.54) | |
| H4:CGTGCG | 0.01 | 0.05 | 0.0317 | 0.4438 | ||
| H5:TGTACG | 0.01 | 0.04 | 0.0909 | |||
| H6:CATATG | 0.04 | 0.03 | 0.6489 | |||
| H7:TGTGCG | 0.05 | 0.02 | 0.1275 | |||
| H8:CATGTA | 0.02 | 0.03 | 0.3929 | |||
| H9:CGTGTA | 0.01 | 0.02 | 0.6998 | |||
| H10:CGCGCG | 0.00 | 0.02 | 0.0894 | |||
| H11:TATGTG | 0.02 | 0.01 | 0.3297 | |||
| H12:CGCGCA | 0.01 | 0.01 | 0.8976 | |||
| H13:CGTACG | 0.01 | 0.02 | 0.4630 | |||
| H14:CATGCG | 0.00 | 0.01 | 0.2656 | |||