Table 3 of Lu, Mol Vis 2010; 16:1-6. Table 3 of Lu, Mol Vis 2010; 16:1-6.
Table 3. Association between subphenotypes of AMD ANS SNPS in SERPING1 in the Han Chinese subject group.
SNP (risk allele) |
Physical location (Chr.11)* |
Phenotype |
Genotype count |
Allele frequency |
HWE |
Trend p-value |
||
|---|---|---|---|---|---|---|---|---|
| rs2511990 (T) | 57119284 | CVN+Drusen | CC:211 | CT:50 | TT:10 | 0.13 | 0.003 | 0.59 |
| CNV | CC:148 | CT:35 | TT:10 | 0.14 | 0.002 | 0.3 | ||
| Drusen | CC:63 | CT:15 | TT:0 | 0.1 | 0.643 | 0.47 | ||
| Control | CC:226 | CT:51 | TT:8 | 0.12 | 0.068 | |||
| rs1005510 (G) | 57123798 | CVN+Drusen | AA:140 | AG:117 | GG:15 | 0.27 | 0.135 | 0.44 |
| CNV | AA:101 | AG:81 | GG:12 | 0.27 | 0.724 | 0.49 | ||
| Drusen | AA:39 | AG:36 | GG:3 | 0.27 | 0.312 | 0.58 | ||
| Control | AA:134 | AG:131 | GG:16 | 0.29 | 0.087 | |||
| rs11546660 (C) | 57124043 | CVN+Drusen | TT:249 | CT:21 | CC:0 | 0.04 | 0.506 | 0.05 |
| CNV | TT:178 | CT:16 | CC:0 | 0.04 | 0.836 | 0.1 | ||
| Drusen | TT:71 | CT:5 | CC:0 | 0.03 | 0.957 | 0.13 | ||
| Control | TT:245 | CT:35 | CC:1 | 0.07 | 0.978 | |||
| rs2511989 (A) | 57134901 | CVN+Drusen | GG:198 | AG:57 | AA:5 | 0.13 | 0.706 | 0.76 |
| CNV | GG:147 | AG:42 | AA:5 | 0.13 | 0.644 | 0.61 | ||
| Drusen | GG:51 | AG:15 | AA:0 | 0.08 | 0.298 | 0.77 | ||
| Control | GG:215 | AG:63 | AA:3 | 0.12 | 0.791 | |||
| rs2511988 (C) | 57135746 | CVN+Drusen | TT:155 | CT:103 | CC:14 | 0.25 | 0.557 | 0.99 |
| CNV | TT:110 | CT:73 | CC:11 | 0.24 | 0.971 | 0.89 | ||
| Drusen | TT:45 | CT:30 | CC:3 | 0.23 | 0.763 | 0.77 | ||
| Control | TT:155 | CT:118 | CC:9 | 0.24 | 0.025 | |||
| rs4926 (A) | 57138565 | CVN+Drusen | GG:201 | AG:65 | AA:6 | 0.14 | 0.784 | 0.43 |
| CNV | GG:147 | AG:42 | AA:5 | 0.13 | 0.644 | 0.7 | ||
| Drusen | GG:54 | AG:23 | AA:1 | 0.16 | 0.689 | 0.25 | ||
| Control | GG:209 | AG:63 | AA:3 | 0.13 | 0.766 | |||