Figure 8. Effect of DEX and CsA on involvement of TLR3 signaling systems in HSV-1 infection of HCECs. HCECs were cultured in the presence or absence of DEX (10^-5 M) and inoculated with 1,000 MOI of HSV-1 for 24 h. Real-time PCR shows that IFN-β and TLR3 expression is down-regulated by DEX. IL-6 and IL-8 are also down-regulated, although the decrease of IL-8 was not statistically significant. (*p<0.05)