Table 2 of D’Souza, Mol Vis 2009; 15:906-911.

Table 2. Comparison of lectin binding of drusen, RPE, Bruch’s membrane, and photoreceptors in AMD

Lectin Drusen RPE Bruch’s RC CC Rod OS Cone OS RM CM
CON A 3 3 3 2 0 3 3 3 3
PSA 3 3 3 1 0 3 3 3 3
ePHA 3 3 3 1 0 3 3 3 3
lPHA 0 0 0 0 0 0 0 0 0
SNA-1 4 (4) 4 (4) 4 (4) 1 (0) 0 (0) 4 (0) 4 (0) 0 (0) 0 (0)
MAA 3 (1) 3 (0) 0 (0) 1 (0) 0 (0) 3 (3) 3 (3) 3 (3) 3 (3)
LFA 3 (0) 1 (0) 0 (0) 1 (0) 1 (0) 3 (0) 3 (0) 1 (0) 1 (0)
WGA 2 (2) 2 (0) 2 (0) 0 (0) 0 (0) 2 (0) 2 (0) 2 (0) 2 (0)
DSA 4 4 4 0 0 3 3 2 2
STA 4 4 4 1 1 3 3 1 2
SBA 0 (2) 0 (2) 0 (2) 0 (0) 0 (0) 0 (1) 0 (1) 0 (0) 0 (0)
DBA 0 0 0 0 0 0 0 0 0
WFA 0 0 0 0 0 0 3 0 0
AHA 0 (2) 0 (2) 0 (1) 0 (1) 0 (0) 0 (3) 2 (3) 0 (3) 2 (3)
MPA 2 0 0 1 1 2 2 3 3
Jac 3 (2) 3 (2) 3 (2) 3 (2) 3 (2) 4 (3) 4 (3) 4 (3) 4 (3)
BSA-1B4 0 0 0 0 0 0 0 0 0
ECA 0 (3) 0 (2) 0 (2) 0 (0) 0 (0) 0 (3) 0 (3) 0 (3) 0 (3)
UEA-1 0 0 0 0 0 0 0 0 0

Key: 0 indicates no binding, 1indicates weak, 2=moderate, 3=moderately strong and 4=intense binding; results in brackets indicate intensity of binding after neuraminidase pretreatment. Abbreviations: RC is rod cytoplasm, CC is cone cytoplasm, RM is rod cell membrane, CM is cone cell membrane, OS is outer segments.

D’Souza, Mol Vis 2009; 15:906-911. http://www.molvis.org/molvis/v15/a94

©2009 Molecular Vision http://www.molvis.org/molvis/

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