Figure 1. Comparison of the lectin-binding pattern of drusen, RPE, Bruch’s membrane, and photoreceptors. A: PSA binds outer segments and cell membranes of both cones (dotted arrow) and rods (solid arrow) strongly. B: PSA binds drusen (white arrow) and Bruch’s membrane (yellow arrow) strongly. C: MPA binds outer segments and cell membranes of both cones (dotted arrow) and rods (solid arrow) with moderate intensity. D: MPA binds drusen (white arrow) and Bruch’s membrane (yellow arrow) with moderate intensity. E: AHA without pretreatment with neuraminidase binds outer segments and cell membranes of cones (dotted arrow) but not rods. F: AHA without pretreatment with neuraminidase does not bind drusen (arrow) or Bruch’s membrane. G: After pretreatment with neuraminidase, AHA binds outer segments and cell membranes of both cones (dotted arrow) and rods (solid, black arrow) strongly and (H) drusen (white arrow) with moderate intensity. Arrowhead indicates RPE. Original magnification is 600×