Table 2 of Jia, Mol Vis 2009; 15:89-98.

Table 2. OPTN and WDR36 polymorphisms investigated in the present study.

 
Gene
Sequence change		  
Codon change		 Allele frequency (%) Genotype frequency
POAG (n=352) Control (n=400) POAG (n=176) Control (n=200)
OPTN c.603 T>A M98K 39 (11.08) 48 (12) 3/33/140 3/42/155
OPTN c.1944 G>A R545Q 12 (3) 13 (3.25) 0/12/164 1/11/188
OPTN IVS5+38 T>G - 118 (33.5) 121 (30.25) 17/84/75 14/93/93
OPTN IVS8 −53 T>C - 27 (7.67) 24 (6) 1/25/150 1/22/177
OPTN IVS15+10G>A - 8 (2.27) 7 (1.75) 0/8/168 0/7/193
WDR36 IVS 5+30 C>T - 134 (38.1) 170 (42.5) 22/90/64 33/104/63

Allelic and genotypic frequencies of the five candidate SNPs in the present study were shown in the table. As only one WDR36 SNP was selected, this SNP was also presented in this table. The “-” represents non-coding polymorphism. The numbers under “Genotype frequency” are the counts of homozygotes, heterozygotes, and wildtype.

Jia, Mol Vis 2009; 15:89-98. http://www.molvis.org/molvis/v15/a9

©2009 Molecular Vision http://www.molvis.org/molvis/

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