Figure 4 of Zhao, Mol Vis 2009; 15:826-832.

Figure 4. Analysis of the missense mutation in exon 50. A: The alignment of the FBN1 sequence with the corresponding segments in diverse species is shown. The cysteine is conserved in FBN1 proteins from several species. The sequence was selected from the UniProt Knowledge base. B: Structure analysis of the transforming growth factor-binding protein-like domains (8-Cys/TB) in human FBN1. α-helices and β-strands are shown with red and brown colors. The two residues (C2061 and C2083) are colored green. The disulfide bond is represented with a dotted line.