Table 2 of Kirwan, Mol Vis 2009; 15:76-88. Table 2 of Kirwan, Mol Vis 2009; 15:76-88.
Table 2. Extracellular matrix (ECM) probe sets (genes) that were differentially expressed in POAG LC cells versus normal LC cells.
| PROBE ID | GENE | Mean normal LC array signal (n=2) |
Mean POAG LC array signal (n=2) |
SLR (n=2) |
|---|---|---|---|---|
| 210809_s_at | osteoblast specific factor 2 (periostin) | 7.7 | 10.7 | 3.0 |
| 203881_s_at | dystrophin | 5.5 | 7.5 | 2.0 |
| 205524_s_at | cartilage linking protein 1 | 4.7 | 6.5 | 1.8 |
| 201150_s_at | tissue inhibitor of metalloproteinase 3 (TIMP-3) | 7.3 | 8.6 | 1.3 |
| 215646_s_at | chondroitin sulfate proteoglycan 2 (versican) | 7.3 | 8.4 | 1.2 |
| 202363_at | sparc/osteonectin, cwcv and kazal-like domains proteoglycan | 8.0 | 9.1 | 1.1 |
| 211571_s_at | chondroitin sulfate proteoglycan 2 (versican) | 7.8 | 8.8 | 1.1 |
| 201110_s_at | thrombospondin 1 | 8.8 | 9.6 | 0.8 |
| 204298_s_at | lysyl oxidase | 9.5 | 10.2 | 0.7 |
| 201842_s_at | EGF-containing fibulin-like extracellular matrix protein 1 | 9.8 | 10.4 | 0.6 |
| 201506_at | transforming growth factor, beta-induced, 68 kDa | 11.1 | 11.7 | 0.6 |
| 202311_s_at | collagen, type I, alpha 1 | 8.7 | 9.2 | 0.6 |
| 212667_at | secreted protein, acidic, cysteine-rich (osteonectin) | 10.1 | 10.6 | 0.6 |
| 212488_at | collagen, type V, alpha 1 | 9.6 | 10.1 | 0.5 |
| 209278_s_at | tissue factor pathway inhibitor 2 | 6.9 | 7.4 | 0.5 |
| 204320_at | collagen, type XI, alpha 1 | 6.8 | 7.3 | 0.5 |
| 205200_at | tetranectin (plasminogen binding protein) | 9.1 | 7.6 | −1.4 |
| 209081_s_at | collagen, type XVIII, alpha 1 | 7.5 | 6.1 | −1.3 |
| 203886_s_at | fibulin 2 | 8.1 | 7.1 | −1.0 |
| 211343_s_at | collagen, type XIII, alpha 1 | 5.7 | 4.8 | −1.0 |
| 209335_at | decorin | 7.7 | 6.9 | −0.9 |
| 202995_s_at | fibulin 1 | 6.2 | 5.5 | −0.7 |
| 212713_at | microfibrillar-associated protein 4 | 7.2 | 6.5 | −0.7 |