Table 3 of Tolppanen, Mol Vis 2009; 15:762-770.

Table 3. Associations of the TNMD haplotypes with total AMD (exudative and atrophic) and exudative AMD in women.


Markers
Frequency		 Total AMD Exudative AMD
OR (95% CI) p OR (95% CI) p
Haploblock 1
rs11798018 rs5966709





A G
0.437



C T
0.329 0.821 (0.541- 1.244) 0.35 0.918 (0.618–1.365) 0.674
C G
0.23 0.921 (0.627–1.353) 0.681 0.853 (0.557–1.306) 0.465
Haploblock 2
rs2073163 rs1155974





T C
0.637



C T
0.287 1.411 (0.972–2.047) 0.319 1.431 (0.979–2.091) 0.064
Markers associated with AMD in women
rs7890586 rs2073163 rs1155974




G T C 0.513



G C T 0.288 1.318 (0.875–1.986) 0.187 1.330 (0.877–2.017) 0.18
A T C 0.084 0.487 (0.241–0.986) 0.046 0.475 (0.226–0.999) 0.05

Haploblocks 1 and 2 are defined on the basis of solid spine of LD. In addition, a 3-marker haplotype was constructed of those markers that were associated with AMD in women. The haplotype analyses did not reveal a haplotype that would explain the results substantially better than the single-marker analyses. Abbreviations: odds ratio (OR); confidence interval (CI).

Tolppanen, Mol Vis 2009; 15:762-770. http://www.molvis.org/molvis/v15/a78

©2009 Molecular Vision http://www.molvis.org/molvis/

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