Table 2 of Narendra, Mol Vis 2009; 15:731-736. Table 2 of Narendra, Mol Vis 2009; 15:731-736.
Table 2. Sequence Alterations Identified in CFHR5.
Exon |
Sequence change |
Protein change |
Allele frequency AMD patients |
Allele frequency normals |
p value |
|---|---|---|---|---|---|
| 4 | GAC→GAT | Asp169Asp | 1/1278=0.001% | 18/1326=0.014% | p<0.0001 |
| 7 | CGT→CAT | Arg356His | 20/1278=0.016% | 9/1326=0.007% | p=0.039 |
| 7 | GTA→CTA | Val379Leu | 0/1278=0.0% | 3/1326=0.002% | p=0.250 |
| 10 | ATG→AGG | Met514Arg | 0/1278=0.0% | 1/1326=0.001% | p=1.000 |
| 10 | TGT→TGA | Cys568Ter | 0/1278=0.0% | 3/1326=0.002% | p=0.250 |