Figure 1. Schematic representation of the genomic structures of the genes in the CFH gene family. The CFH family is composed of several distinct proteins that lie in a gene cluster on chromosome 1. Structurally, these proteins are similar. They each contain several functional domains called short consensus repeats (SCRs), which are drawn as ovals in this illustration. The interacting proteins for some of these SCRs have been determined and are shown at the top. Abbreviations: C reactive protein (CRP); heparin (Hep).