Figure 7. PmacI digestion of PCR products with for the c.1072T>C transition. PCR products in individuals with the c.1072T>C transition were digested into 337 bp and 357 bp and into only 357bp in individuals without the c.1072T>C transition. A: Members of the Chinese family with MCD. PCR products from individuals II:3, III:2, III:4, III:5, III:6 and IV:2 with c.1072T>C transition were digested into 337bp and 357bp, other members without c.1072T>C transition only had a 357bp segment. B: Part of 100 control subjects. Control subjects without c.1072T>C transition only had a 357bp segment. U indicates undigested PCR product, and P indicates one patient in the Chinese family with MCD.