Figure 7. Evolution of the choroidal neovascularization reaction in young adult (group III) and old mice (group IV) as assessed on flat mounts. A: Choroidal neovascularization (CNV) reaction is still detected eight months after photocoagulation and is more important in 1-year-old mice during all tested time points. The difference between the two groups is significant on day 7 (p=0.028) and on month 8 (p=0.0094). B: The mean CNV area (during the first two weeks after photocoagulation) is larger in the 1-year-old mice; the difference is highly statistically significant according to t-test.