Figure 4. Immunohistochemical studies for CD163 in the iris and choroid whole mounts at different times after LPS injection. A–E: CD163⁺ resident tissue macrophages in the control rats (A) and at 6 h (B), 12 h (C), 24 h(D), and 48h (E) after LPS injection in the iris. Note the increase in the number of round-pleiomorphic cells between 12 and 48 h and the numerous small round cells (arrow) at 48 h (E). The large dendritiform CD163⁺ cells were unchanged in the peripheral choroid between 0 h (F) and 12 h (G). Original magnification: A–E 200X; F,G 400X.