Table 6 of Sharma, Mol Vis 2009; 15:60-69.


Table 6. Comparison between processes in diabetic and non-diabetic aqueous humor.

Number Processes Size Target Pathways p value zScore
Common
1 Locomotory behavior (42.6%), G-protein coupled receptor protein signaling pathway (51.1%), cell surface receptor linked signal transduction (66.0%) 50 13 10 8.58e−29 57.35
2 Response to external stimulus (56.2%), response to wounding (47.9%), response to stimulus (79.2%) 50 14 1 1.73e−31 61.78
3 Lipid transport (29.4%), sterol transport (23.5%), cholesterol transport (23.5%) 50 12 0 3.44e−27 57.78
4 Immune system process (54.0%), organ development (68.0%), response to stimulus (74.0%) 50 13 0 8.58e−29 57.35
5 Response to stimulus (75.0%), response to wounding (40.9%), response to external stimulus (47.7%) 50 7 6 4.60e−14 31.76
Unique for Diabetes Samples
1 Response to external stimulus (50.0%), response to wounding (41.3%), cell surface receptor linked signal transduction (58.7%) 50 4 0 1.33e−11 51.55
2 Taxis (100.0%), chemotaxis (100.0%), locomotory behavior (100.0%) 5 1 0 6.01e−04 40.77
Unique for Normal Samples
1 Response to wounding (37.2%), response to stimulus (69.8%), intracellular signaling cascade (51.2%) 50 8 0 1.68e−21 67.49
2 Response to external stimulus (53.8%), response to wounding (46.2%), cell surface receptor linked signal transduction (64.1%) 44 5 0 8.36e−13 44.93
3 Cellular di-, tri-valent inorganic cation homeostasis (100.0%), di-, tri-valent inorganic cation homeostasis (100.0%), cellular cation homeostasis (100.0%) 27 2 0 3.28e−06 37.72