Figure 3. Analysis of caspase-3, -8, and -9 activation. HCE cells were incubated with PBS (clear square) or HMW-HA (black square) and
irradiated with various doses (0, 25, 75, and 150 mJ/cm2) of UVB. Caspase-3 (A), -8 (B), and -9 (C) activations were determined 24 h after irradiation. Data are mean±SD of three independent experiments. Differences were
significant at p<0.05 (one asterisk), p<0.01 (two asterisks), and p<0.001 (three asterisks) compared to the PBS group of each
UVB dose.