Table 2 of Chen, Mol Vis 2009; 15:563-576. Table 2 of Chen, Mol Vis 2009; 15:563-576.
Table 2. Profile of anterior segment immune cells in Aire-sufficient versus Aire-deficient mice.
| Immune cell |
Genotype |
Central Cornea | Limbus | Conjunctiva | ||||||
| 4 wk | 8 wk | 16 wk | 4 wk | 8 wk | 16 wk | 4 wk | 8 wk | 16 wk | ||
| CD4+ | Aire+/− | 1.03±2.06 | 2.26±2.62 | 8.34±9.84 | 13.96±21.98 | 2.62±3.80 | 18.85±22.99 | 50.46±47.73 | 111.58±60.24 | 55.24±76.48 |
| Aire−/− | 4.06±3.73 | 41.53±38.61 | 113.97±122.86 | 455.42±657.03 | 854.13±455.42 | 235.55±218.41 | 332.03±247.28 | 611.79±602.86 | 411.92±518.64 | |
| CD8+ | Aire+/− | 0±0 | 0±0 | 0±0 | 0±0 | 3.123±6.25 | 6.94±13.89 | 6.39±12.77 | 0.72±1.43 | 0±0 |
| Aire−/− | 3.43±6.86 | 16.33±17.11 | 67.45±104.51 | 551.35±928.04 | 247.58±144.59 | 151.84±224.85 | 289.6±380.37 | 355.02±204.18 | 38.13±46.22 | |
| CD11c+ | Aire+/− | 0.18±0.36 | 0.06±0.13 | 17.44±24.26 | 58.79±57.03 | 24.12±48.00 | 27.59±18.75 | 79.83±38.66 | 80.5±71.92 | 117.86±116.45 |
| Aire−/− | 11.57±8.83 | 21.26±18.95 | 230.96±239.18 | 676.25±607.16 | 906.94±401.30 | 881.14±567.89 | 382.78±205.78 | 403.39±353.03 | 565.99±608.88 | |
| I-A[d]+ | Aire+/− | 0±0 | 0.322±0.645 | 0.45±0.9 | 26.95±36.69 | 22.47±20.22 | 44.57±34.75 | 213.91±70.22 | 181.41±92.18 | 85.84±69.44 |
| Aire−/− | 24.90±29.25 | 17.85±15.30 | 210.99±19.59 | 714.18±1329.62 | 1746.79±845.55 | 687.06±401.39 | 543.61±557.55 | 552.40±264.02 | 1280.06±845.53 | |