Figure 2 of Chen, Mol Vis 2009; 15:563-576.

Figure 2. Time course of goblet cell density in Aire+/− versus Aire−/− mice. A: Periodic acid–Schiff staining revealed abundant goblet cells (arrow) in Aire+/− at all time points (representative example shown) and in Aire−/− at four weeks of age. A gradual decrease in goblet cell density was observed in the conjunctiva of Aire−/− mice over time. Bar, 100 μm. B: Time course of goblet cell density is shown as mean±SD. An asterisk indicates that p<0.05, Aire+/− versus Aire−/− at each time point.