Figure 2 of Inoue-Mochita, Mol Vis 2009; 15:495-504.


Figure 2. Iridocorneal histological changes in the RGS2−/− mice. A: Iridocorneal histological analysis was performed to examine structural differences in the aqueous humor outflow pathway and ciliary body between the RGS2−/− and wild-type mice. The structural integrity of the trabecular meshwork (TM), ciliary body (CB), and ciliary muscle (CM) were found to be comparable between the two groups of mice. However, the Schlemm’s canal (SC) area was found to be significantly larger in the RGS2−/− mice compared to the littermate wild-type mice. B: Quantitative changes in the SC area between the RGS2−/− and wild-type mice based on Metamorph pixel analysis. Values are shown as mean±SEM (n=6). Asterisk represents p<0.05. Abbreviations: sclera (SCL), retina (RT).