Table 6 of Kozulin, Mol Vis 2009; 15:45-59.

Table 6. Levels of expression of anti-angiogenic genes in developing human retina, p<0.01


Gene title
Gene symbol		 Macula versus surround Macula versus nasal Affymetrix
Probe Set ID
p= DE# (%) p= DE# (%)
pigment epithelium derived factor (serpin peptidase inhibitor, clade F member 1) PEDF 0.003 49.52 0.004 46.62 202283_at
natriuretic peptide precursor B NPPB 0.003 28.57 0.002 33.05 206801_at
collagen, type IV, alpha 2 COL4A2 0.151 −21.16* 0.005 −59.72 211964_at
collagen, type IV, alpha 2 COL4A2 0.033 −35.56* 0.001 −85.44 211966_at

PEDF, NPPB, and COL4A2 were the only anti-angiogenic genes, out of 17 known negative angiogenic regulators, to show significant differential expression between the macula and surrounding retina. Non-significant fold changes (*p>0.01) are indicated.

Kozulin, Mol Vis 2009; 15:45-59. http://www.molvis.org/molvis/v15/a5

©2009 Molecular Vision http://www.molvis.org/molvis/

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