Table 4 of Kozulin, Mol Vis 2009; 15:45-59.

Table 4. Highly represented clusters of genes in the differential expression data

Gene Ontology ID Biological Process Number of genes
Macula versus surround Macula versus nasal
GO:0008152 metabolism 1,520 1,059
GO:0065007 biological regulation 935 883
GO:0010467 gene expression 661 253
GO:0016043 cellular component organization and biogenesis 569 537
GO:0051179 localization 370 532
GO:0007154 cell communication 368 669
n/a# cell proliferation and division 358 355
GO:0032502 development 334 612
GO:0007155 cell adhesion 162 176
GO:0003008 system process 147 170
GO:0050896 response to stimulus 126 136
GO:0046903 secretion 81 64
GO:0040007 growth 64 66
GO:0050953 sensory perception of light stimulus 51 51
GO:0007059 chromosome segregation 30 33

The high representation of genes related to biological processes such as “metabolism” likely reflects the more advanced state of macular development relative to non-macular retina. The sharp (hash mark) indicates that this term is a combination of cell cycle (GO:0007049), cell proliferation (GO:0008283) and cell division (GO:0051301); Abbreviation: Gene Ontology (GO).

Kozulin, Mol Vis 2009; 15:45-59. http://www.molvis.org/molvis/v15/a5

©2009 Molecular Vision http://www.molvis.org/molvis/

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