Figure 1. In vitro cell culture models. These models were used for analyzing paracrine interactions between retinal capillary endothelial and Müller cells. A: In the transfilter co-culture, TR-MUL5 cells were situated on the basolateral aspect of TR-iBRB2 cells monolayer as might occur in vivo. B: The fivefold concentrated conditioned medium of TR-MUL5 cells (MUL-CM) was applied to TR-iBRB2 cells.