Molecular Vision: Meng, Mol Vis 2009; 15:386-392. Table 3

Table 3. Genotype and allele frequencies of SNPs PD-1.3, PD-1.5, and PD-1.6 in VKH patients and healthy controls.

PDCD1 SNPs	VKH patients (%)	Healthy controls (%)	χ²	p	pc	Odds ratio (95%CI)
PD-1.3
Genotype
GG	247 (100)	289 (100)	—	—	—	—
AG	—	—
AA	—	—
Allele
G	494 (100)	578 (100)	—	—	—	—
A	—	—
PD-1.5
Genotype
CC	131 (53.0)	176 (60.9)	6.786	0.034	0.306	—
CT	91 (36.8)	99 (34.3)
TT	25 (10.1)	14 (4.8)
Allele
C	353 (71.5)	451 (78.0)	6.132	0.013	0.078	0.705 (0.534–0.930)
T	141 (28.5)	127 (22.0)
PD-1.6
Genotype
AA	124 (50.2)	136 (47.1)	5.171	0.075	—	—
AG	108 (43.7)	119 (41.2)
GG	15 (6.1)	34 (11.7)
Allele
A	356 (72.1)	391 (67.6)	2.413	0.12	—	1.232 (0.947–1.603)
G	138 (27.9)	187 (32.4)

The distribution of genotype frequencies of each SNP in the healthy controls did not show significant deviation from the Hardy-Weinberg equilibrium. The frequency of the C allele and CC genotype of PD-1.5 were lower in VKH patients than in healthy controls, but the differences were not statistically significant following the Bonferroni correction. The genotype and allele frequencies of PD-1.3 and PD-1.6 in VKH patients were not different from those in healthy controls. Only the GG genotype and the G allele of PD-1.3 were identified in all patients and controls