Figure 1. Pedigree of the Chinese cataract family and haplotype analysis. Squares and circles indicate males and females, respectively. Solid and open symbols denote affected and unaffected individuals, respectively. Haplotype analysis shows the segregation of five microsatellite markers on chromosome 12. The physical distance of microsatellite markers and the disease gene have been given in the top left corner. The haplotype of the disease-bearing chromosome is indicated by black bar.