Table 3 of Mattes, Mol Vis 2009; 15:343-348.

Table 3. PEDF genotypes in exudative AMD patients and controls.



Polymorphism

Genotype		 Exudative
AMD patients
(n=269)
Controls
(n=155)

p
Met72Thr (rs1136287) Met/Met 111 (41.3%) 64 (41.3%) 0.81
Met/Thr 123 (45.7%) 74 (47.7%)
Thr/Thr 35 (13.0%) 17 (11.0%)
MAF 0.359 0.348 0.76
−5736T>C (rs12150053) TT 108 (40.1%) 67 (43.2%) 0.71
TC 117 (43.5%) 61 (39.4%)
CC 44 (16.4%) 27 (17.4%)
MAF 0.381 0.371 0.77
−5304C>T (rs12948385) CC 108 (40.1%) 67 (43.2%) 0.71
CT 117 (43.5%) 61 (39.4%)
TT 44 (16.4%) 27 (17.4%)
MAF 0.381 0.371 0.77

Data indicate the number of eyes with and without exudative age-related macular degeneration (AMD), respectively. Numbers are given as n (%). Neither PEDF genotypes nor minor allele frequencies (MAF) were significantly associated with exudative AMD.

Mattes, Mol Vis 2009; 15:343-348. http://www.molvis.org/molvis/v15/a35

©2009 Molecular Vision http://www.molvis.org/molvis/

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