Figure 9. Multisequence alignment of the human CYP1B1 protein with the CYP1B1 protein from different species. Underlined red amino acids show the conserved residues (when mutated) causing the primary congenital glaucoma phenotype. Red colored amino acid shows the non-conservation of glutamic acid at this locus in Zebrafish CYP1B1. Blue-colored amino acids show the less conserved residues in CYP1B1 protein from different species.