Molecular Vision: Yang, Mol Vis 2009; 15:312-318. Table 2

Table 2. Markers yielding a two-point LOD score over 1.0 from a genome-wide scan.

Markers	LOD score at θ=
Markers	0.00	0.01	0.05	0.10	0.20	0.30	0.40
D1S199	1.43	1.39	1.27	1.11	0.80	0.49	0.22
D3S1580	2.03	1.99	1.82	1.60	1.14	0.67	0.23
D4S406	1.12	1.10	1.00	0.88	0.62	0.38	0.17
D4S1597	1.43	1.39	1.27	1.11	0.80	0.49	0.22
D7S657	2.19	2.14	1.96	1.72	1.24	0.77	0.33
D9S286	1.43	1.39	1.27	1.11	0.80	0.49	0.22
D10S249	1.12	1.10	1.00	0.88	0.62	0.38	0.17
D10S189	2.03	1.98	1.8	1.56	1.08	0.61	0.19
D11S901	1.12	1.10	1.00	0.88	0.62	0.38	0.17
D11S898	1.43	1.39	1.27	1.11	0.80	0.49	0.22
D11S1320	1.43	1.39	1.27	1.11	0.80	0.49	0.22
D11S968	1.43	1.39	1.27	1.11	0.80	0.49	0.22
D13S265	1.12	1.10	1.00	0.88	0.62	0.38	0.17
D14S276	1.43	1.39	1.27	1.11	0.80	0.49	0.22
D14S63	2.03	1.98	1.8	1.56	1.08	0.61	0.19
D14S258	1.12	1.10	1.00	0.88	0.62	0.38	0.17
D16S404	1.12	1.10	1.00	0.88	0.62	0.38	0.17
D16S3046	1.12	1.10	1.00	0.88	0.62	0.38	0.17
D17S1868	1.12	1.10	1.00	0.88	0.62	0.38	0.17
D17S787	2.19	2.15	1.98	1.76	1.30	0.83	0.37
D18S452	1.43	1.39	1.27	1.11	0.80	0.49	0.22
D19S571	1.43	1.39	1.27	1.11	0.80	0.49	0.22

It is common to have several dozen of markers with positive LOD scores in a genome-wide scan in a family of moderate size. A single marker with a LOD score over 1.0 is usually not an indication of suggestive linkage if it is not supported by closely flanking markers. To report all markers with positive LOD scores greater than 1.0 may provide useful clues for subsequent linkage study of other families with arHM. Markers on relevant regions of chromosomes 11, 14, and 17 are highlighted in bold.