Table 4 of Tsironi, Mol Vis 2009; 15:2890-2895.

Table 4. Influence of genotypes on disease susceptibility based on carrier status of risk allele considering dominant or recessive model.

Model MMP-1 (-1607 1G/2G) MMP-3 (-1171 5A/6A)
Allele contrast 1G 2G OR (95%CI)* p 6A 5A OR (95%CI)* p
Controls 240 188 Reference   209 219 Reference  
Patients-XFS/+G 120 64 1.47 (1.03-2.10) 0.04 92 92 0.95 (0.68-1.35) 0.79
Patients-XFS/-G 107 73 1.15 (0.81-1.64) 0.44 79 101 0.75 (0.53-1.06) 0.29
Patients-XFS total 227 137 1.30 (0.98-1.73) 0.07 171 193 0.90 (0.68-1.19) 0.99
Dominant model 1G/- -/- OR (95%CI)* p 5A/- -/- OR(95%CI)* p
Controls 175 39 Reference   160 54 Reference  
Patients-XFS/+G 81 11 1.61 (0.78-3.35) 0.18 67 25 0.89 (0.50-1.53) 0.68
Patients-XFS/-G 77 13 1.33 (0.68-2.65) 0.46 73 17 1.42 (0.74-2.61) 0.25
Patients-XFS total 158 24 1.51 (0.87-2.46) 0.20 140 42 1.09 (0.68-1.65) 0.91
Recessive model 1G/1G 2G/- OR (95%CI)*   p 5A/5A 6A/- OR (95%CI)*   p
Controls 65 149 Reference   59 155 Reference  
Patients-XFS/+G 39 53 0.62 (0.43-0.98) 0.05 25 67 1.04 (0.58-1.73) 0.93
Patients-XFS/-G 30 60 0.90 (0.50-1.48) 0.65 28 62 0.86 (0.49-1.38) 0.57
Patients-XFS total 69 113 0.73 (0.46-1.13) 0.13 53 129 1.03 (0.66-1.54) 0.97

The asterisk indicates that OR was adjusted for age and gender.

Tsironi, Mol Vis 2009; 15:2890-2895. http://www.molvis.org/molvis/v15/a305

©2009 Molecular Vision http://www.molvis.org/molvis/

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