Table 1 of Khan, Mol Vis 2009; 15:2861-2867. Table 1 of Khan, Mol Vis 2009; 15:2861-2867.
Table 1. TNF-α G −308A genotype and allele frequency distribution between patients and controls.
| Controls (126) |
PEXG (122) |
OR (95% CI) |
p (χ2) | |
|---|---|---|---|---|
| Mean age (years) | 44.2±12.3 | 45.3±12.7 | ||
| Gender distribution | ||||
| Males | 81 (64.3%) | 82 (67.2%) | 0.88 (0.50–1.54) | 0.6 (0.24) |
| Female | 45 (35.7%) | 40 (32.8%) | ||
| Genotype and allele frequency distribution | ||||
| Genotypes (Males+Females) | ||||
| GG | 110 (87.3%) | 53 (43.4%) | 8.95 (4.55–17.81) | <0.001 (54.97) |
| GA | 13 (10.3%) | 39 (32.0%) | 0.24 (0.12–0.51) | |
| AA | 3 (2.4%) | 30 (24.6%) | 0.07 (0.02–0.27) | |
| Alleles (Males+Females) | ||||
| G | 233 (92.5%) | 145 (59.4%) | 8.37 (4.78–14.81) | <0.001 (74.61) |
| A | 19 (7.5%) | 99 (40.6%) | ||
| Genotypes (Males) | ||||
| GG | 69 (85.2%) | 36 (43.9%) | 7.35 (3.27–16.79) | <0.001 (33.30) |
| GA | 11 (13.6%) | 27 (32.9%) | 0.32 (0.14–0.75) | |
| AA | 1 (1.2%) | 19 (23.2%) | 0.04 (0.001–0.31) | |
| Alleles (Males) | ||||
| G | 149 (92.0%) | 99(60.4%) | 7.53 (3.79–15.19) | <0.001 (44.74) |
| A | 13 (8.0%) | 65(39.6%) | ||
| Genotypes (Females) | ||||
| GG | 41 (91.1%) | 17 (42.5%) | 13.87 (3.74–56.25) | <0.001 (23.09) |
| GA | 2 (4.4%) | 12 (30.0%) | 0.11 (0.02–0.58) | |
| AA | 2 (4.4%) | 11 (27.5%) | 0.12 (0.02–0.66) | |
| Alleles (Females) | ||||
| G | 84 (93.3%) | 46 (57.5%) | 10.35 (3.78–29.81) | <0.001 (30.22) |
| A | 6 (6.7%) | 34 (42.5%) | ||