Figure 2. The distribution in rat eyes of intravitreally administered fluorescent dye labeled full-length IgG (red). A and B show the distribution of the full-length IgG in the live and post-mortem retina 6 h post intravitreal administration, respectively. More antibodies were observed in the post-mortem retina, compared to the live retina, suggesting the presence of active elimination mechanisms for IgG in the live retina. A, B: Cell nuclei were stained with DAPI (blue). Abbreviations: inner limiting membrane (ILM), ganglion cell layer (GCL), inner plexiform layer (IPL), inner nuclear layer (INL), outer plexiform layer (OPL), outer nuclear layer (ONL), and external limiting membrane (ELM).