Table 3 of Richardson, Mol Vis 2009; 15:2740-2750.


Table 3. Proteins in the albumin-depleted aqueous humor fraction of patients with cataracts identified with high confidence using LC-MS/MS.


Swiss-Prot
number


Protein common name

Plasma
protein

MW
(kDa)

Distinct
sequences
Minimum
peptide
q-value
Peptide sequence
with minimum
q-value
229479 740525A lipoprotein Gln I NF 28 8 3.42E-06 VSFLSALEEYTK
P43652 Afamin Yes 69 3 2.01E-07 DADPDTFFAK
P02763 Alpha-1-acid glycoprotein 1 [1] Yes 24 4 0.00E+00 EQLGEFYEALDCLR
P19652 Alpha-1-acid glycoprotein 2 Yes 24 3 1.42E-07 TLMFGSYLDDEK
P01011 Alpha-1-antichymotrypsin, Isoform 1 Yes 48 7 1.85E-10 AVLDVFEEGTEASAATAVK
P01011 Alpha-1-antichymotrypsin, Isoform 2 Yes 48 3 1.44E-08 LYGSEAFATDFQDSAAAK
P01009 Alpha-1-antitrypsin [1,15] Yes 47 16 0.00E+00 DTEEEDFHVDQVTTVK
P04217 Alpha-1B-glycoprotein Yes 54 2 7.26E-05 CEGPIPDVTFELLR
P25311 Alpha-2-glycoprotein 1, zinc Yes 34 4 3.42E-06 AYLEEECPATLR
P02765 Alpha-2-HS-glycoprotein Yes 39 4 3.93E-06 EHAVEGDCDFQLLK
P01023 Alpha-2-macroglobulin [1] Yes 163 5 1.06E-07 NEDSLVFVQTDK
Q06481 Amyloid-like protein 2, Isoform 1 NF 87 2 1.65E-05 VPYVAQEIQEEIDELLQEQR
Q7KZ97 Antithrombin III variant [1] Yes 53 8 4.50E-06 DDLYVSDAFHK
P02647 Apolipoprotein A-I [1,5] Yes 31 14 6.42E-09 DYVSQFEGSALGK
Q76EI7 Apolipoprotein A-II Yes 3 3 5.70E-08 EPCVESLVSQYFQTVTDYGK
P06727 Apolipoprotein A-IV [1] Yes 45 3 4.82E-06 SLAPYAQDTQEK
P05090 Apolipoprotein D [1] Yes 21 2 3.17E-08 CPNPPVQENFDVNK
P02649 Apolipoprotein E [1] Yes 36 5 4.38E-07 VQAAVGTSAAPVPSDNH
P02749 Beta-2-glycoprotein 1 Yes 38 4 3.37E-06 CSYTEDAQCIDGTIEVPK
P61769 Beta-2-microglobulin [5] Yes 14 3 5.63E-04 VNHVTLSQPK
O94985 Calsyntenin 1 isoform 2 NF 110 2 3.07E-08 AASEFESSEGVFLFPELR
P00450 Ceruloplasmin [1] Yes 122 20 7.16E-08 HYYIGIIETTWDYASDHGEK
P10909 Clusterin [15] Yes 52 13 0.00E+00 EILSVDCSTNNPSQAK
P01024 Complement C3 Yes 187 14 2.12E-07 SGSDEVQVGQQR
P02462 Collagen alpha-1(IV) chain [1] Yes 161 2 0.00E+00 GDPGLKGDK
P0C0L4 Complement C4-A [1] Yes 193 8 1.24E-08 VLSLAQEQVGGSPEK
P00751 Complement factor B, Isoform 1 Yes 86 3 4.68E-06 EAGIPEFYDYDVALIK
P01034 Cystatin C [1,5] Yes 16 4 7.15E-08 ALDFAVGEYNK
Q9UBP4 Dickkopf-related protein 3 NF 38 7 4.75E-11 SAVEEMEAEEAAAK
Q12805 EGF-containing fibulin-like extracellular matrix protein 1 Yes 55 2 4.05E-05 IQCAAGYEQSEHNVCQDIDECTAGTHNCR
P06396 Gelsolin, Isoform 1 Yes 86 7 5.52E-07 PALPAGTEDTAK
P22352 Glutathione peroxidase 3 Yes 26 4 2.10E-06 NSCPPTSELLGTSDR
P00739 Haptoglobin-related protein, Isoform 1 Yes 39 4 5.42E-06 AVGDKLPECEAVCGKPK
Q8IZI0 Hemoglobin beta chain variant Hb-I Toulouse NF 12 7 3.31E-08 VNVDEVGGEALGR
P69905 Hemoglobin subunit alpha [5] Yes 15 5 4.97E-11 VGAHAGEYGAEALER
P68871 Hemoglobin subunit beta [5] Yes 16 9 3.31E-08 VNVDEVGGEALGR
A0N071 Hemoglobin subunit delta [5] Yes 16 4 7.12E-06 VLGAFSDGLAHLDNLK
P02790 Hemopexin Yes 52 14 2.24E-08 GECQAEGVLFFQGDR
P04196 Histidine-rich glycoprotein Yes 60 3 2.98E-06 DSPVLIDFFEDTER
Q0VAC5 HP protein NF 38 7 1.10E-06 TEGDGVYTLNNEK
P10745 Interphotoreceptor retinoid-binding protein NF 135 11 2.03E-07 TAVDLESLASQLTADLQEVSGDHR
Q2XP30 Mutant beta-globin NF 2 2 4.24E-05 VHLTPEEK
Q9UBM4 Opticin NF 37 2 1.51E-07 EGDSFEVLPLR
P36955 Pigment epithelium-derived factor Yes 46 12 0.00E+00 DTDTGALLFIGK
P05155 Plasma protease C1 inhibitor Yes 55 4 2.98E-06 LEDMEQALSPSVFK
Q9P173 PRO2275 NF 13 5 3.20E-10 VFSNGADLSGVTEEAPLK
P41222 Prostaglandin-H2 D-isomerase Yes 21 10 0.00E+00 EAQVSVQPNFQQDK
P02787 Serotransferrin [1] Yes 77 50 2.57E-11 FDEFFSEGCAPGSK
P02766 Transthyretin [1,15,16] Yes 16 12 2.24E-08 KAADDTWEPFASGK
P68871 Unnamed protein product NF 16 8 3.31E-08 VNVDEVGGEALGR
P02774 Vitamin D-binding protein [1,16] Yes 53 7 3.22E-08 VPTADLEDVLPLAEDITNILSK