Table 3 of Richardson, Mol Vis 2009; 15:2740-2750.
Table 3. Proteins in the albumin-depleted aqueous humor fraction of patients with cataracts identified with high confidence using LC-MS/MS.
Swiss-Prot number |
Protein common name |
Plasma protein |
MW (kDa) |
Distinct sequences |
Minimum peptide q-value |
Peptide sequence with minimum q-value |
|---|---|---|---|---|---|---|
| 229479 | 740525A lipoprotein Gln I | NF | 28 | 8 | 3.42E-06 | VSFLSALEEYTK |
| P43652 | Afamin | Yes | 69 | 3 | 2.01E-07 | DADPDTFFAK |
| P02763 | Alpha-1-acid glycoprotein 1 [1] | Yes | 24 | 4 | 0.00E+00 | EQLGEFYEALDCLR |
| P19652 | Alpha-1-acid glycoprotein 2 | Yes | 24 | 3 | 1.42E-07 | TLMFGSYLDDEK |
| P01011 | Alpha-1-antichymotrypsin, Isoform 1 | Yes | 48 | 7 | 1.85E-10 | AVLDVFEEGTEASAATAVK |
| P01011 | Alpha-1-antichymotrypsin, Isoform 2 | Yes | 48 | 3 | 1.44E-08 | LYGSEAFATDFQDSAAAK |
| P01009 | Alpha-1-antitrypsin [1,15] | Yes | 47 | 16 | 0.00E+00 | DTEEEDFHVDQVTTVK |
| P04217 | Alpha-1B-glycoprotein | Yes | 54 | 2 | 7.26E-05 | CEGPIPDVTFELLR |
| P25311 | Alpha-2-glycoprotein 1, zinc | Yes | 34 | 4 | 3.42E-06 | AYLEEECPATLR |
| P02765 | Alpha-2-HS-glycoprotein | Yes | 39 | 4 | 3.93E-06 | EHAVEGDCDFQLLK |
| P01023 | Alpha-2-macroglobulin [1] | Yes | 163 | 5 | 1.06E-07 | NEDSLVFVQTDK |
| Q06481 | Amyloid-like protein 2, Isoform 1 | NF | 87 | 2 | 1.65E-05 | VPYVAQEIQEEIDELLQEQR |
| Q7KZ97 | Antithrombin III variant [1] | Yes | 53 | 8 | 4.50E-06 | DDLYVSDAFHK |
| P02647 | Apolipoprotein A-I [1,5] | Yes | 31 | 14 | 6.42E-09 | DYVSQFEGSALGK |
| Q76EI7 | Apolipoprotein A-II | Yes | 3 | 3 | 5.70E-08 | EPCVESLVSQYFQTVTDYGK |
| P06727 | Apolipoprotein A-IV [1] | Yes | 45 | 3 | 4.82E-06 | SLAPYAQDTQEK |
| P05090 | Apolipoprotein D [1] | Yes | 21 | 2 | 3.17E-08 | CPNPPVQENFDVNK |
| P02649 | Apolipoprotein E [1] | Yes | 36 | 5 | 4.38E-07 | VQAAVGTSAAPVPSDNH |
| P02749 | Beta-2-glycoprotein 1 | Yes | 38 | 4 | 3.37E-06 | CSYTEDAQCIDGTIEVPK |
| P61769 | Beta-2-microglobulin [5] | Yes | 14 | 3 | 5.63E-04 | VNHVTLSQPK |
| O94985 | Calsyntenin 1 isoform 2 | NF | 110 | 2 | 3.07E-08 | AASEFESSEGVFLFPELR |
| P00450 | Ceruloplasmin [1] | Yes | 122 | 20 | 7.16E-08 | HYYIGIIETTWDYASDHGEK |
| P10909 | Clusterin [15] | Yes | 52 | 13 | 0.00E+00 | EILSVDCSTNNPSQAK |
| P01024 | Complement C3 | Yes | 187 | 14 | 2.12E-07 | SGSDEVQVGQQR |
| P02462 | Collagen alpha-1(IV) chain [1] | Yes | 161 | 2 | 0.00E+00 | GDPGLKGDK |
| P0C0L4 | Complement C4-A [1] | Yes | 193 | 8 | 1.24E-08 | VLSLAQEQVGGSPEK |
| P00751 | Complement factor B, Isoform 1 | Yes | 86 | 3 | 4.68E-06 | EAGIPEFYDYDVALIK |
| P01034 | Cystatin C [1,5] | Yes | 16 | 4 | 7.15E-08 | ALDFAVGEYNK |
| Q9UBP4 | Dickkopf-related protein 3 | NF | 38 | 7 | 4.75E-11 | SAVEEMEAEEAAAK |
| Q12805 | EGF-containing fibulin-like extracellular matrix protein 1 | Yes | 55 | 2 | 4.05E-05 | IQCAAGYEQSEHNVCQDIDECTAGTHNCR |
| P06396 | Gelsolin, Isoform 1 | Yes | 86 | 7 | 5.52E-07 | PALPAGTEDTAK |
| P22352 | Glutathione peroxidase 3 | Yes | 26 | 4 | 2.10E-06 | NSCPPTSELLGTSDR |
| P00739 | Haptoglobin-related protein, Isoform 1 | Yes | 39 | 4 | 5.42E-06 | AVGDKLPECEAVCGKPK |
| Q8IZI0 | Hemoglobin beta chain variant Hb-I Toulouse | NF | 12 | 7 | 3.31E-08 | VNVDEVGGEALGR |
| P69905 | Hemoglobin subunit alpha [5] | Yes | 15 | 5 | 4.97E-11 | VGAHAGEYGAEALER |
| P68871 | Hemoglobin subunit beta [5] | Yes | 16 | 9 | 3.31E-08 | VNVDEVGGEALGR |
| A0N071 | Hemoglobin subunit delta [5] | Yes | 16 | 4 | 7.12E-06 | VLGAFSDGLAHLDNLK |
| P02790 | Hemopexin | Yes | 52 | 14 | 2.24E-08 | GECQAEGVLFFQGDR |
| P04196 | Histidine-rich glycoprotein | Yes | 60 | 3 | 2.98E-06 | DSPVLIDFFEDTER |
| Q0VAC5 | HP protein | NF | 38 | 7 | 1.10E-06 | TEGDGVYTLNNEK |
| P10745 | Interphotoreceptor retinoid-binding protein | NF | 135 | 11 | 2.03E-07 | TAVDLESLASQLTADLQEVSGDHR |
| Q2XP30 | Mutant beta-globin | NF | 2 | 2 | 4.24E-05 | VHLTPEEK |
| Q9UBM4 | Opticin | NF | 37 | 2 | 1.51E-07 | EGDSFEVLPLR |
| P36955 | Pigment epithelium-derived factor | Yes | 46 | 12 | 0.00E+00 | DTDTGALLFIGK |
| P05155 | Plasma protease C1 inhibitor | Yes | 55 | 4 | 2.98E-06 | LEDMEQALSPSVFK |
| Q9P173 | PRO2275 | NF | 13 | 5 | 3.20E-10 | VFSNGADLSGVTEEAPLK |
| P41222 | Prostaglandin-H2 D-isomerase | Yes | 21 | 10 | 0.00E+00 | EAQVSVQPNFQQDK |
| P02787 | Serotransferrin [1] | Yes | 77 | 50 | 2.57E-11 | FDEFFSEGCAPGSK |
| P02766 | Transthyretin [1,15,16] | Yes | 16 | 12 | 2.24E-08 | KAADDTWEPFASGK |
| P68871 | Unnamed protein product | NF | 16 | 8 | 3.31E-08 | VNVDEVGGEALGR |
| P02774 | Vitamin D-binding protein [1,16] | Yes | 53 | 7 | 3.22E-08 | VPTADLEDVLPLAEDITNILSK |