Table 6 of Fang, Mol Vis 2009; 15:2710-2719.

Table 6. Haplotype analysis of VEGFR-2


SNP 1
SNP 2
SNP 3
SNP 4
SNP 5		 Frequency
in cases		 Frequency
in controls
p-value
Block 1
rs1531289 rs17709898 rs12505758 rs13109660 rs1870377      
G A T A T 0.351 0.304 0.066
G G T G A 0.217 0.257 0.087
A A T G T 0.182 0.182 0.992
G G T G T 0.105 0.123 0.302
A A C G T 0.113 0.102 0.514
G G T A T 0.015 0.008 0.248
Block 2
rs7654599 rs17085326            
T C       0.516 0.51 0.835
C C       0.406 0.415 0.731
T T       0.079 0.075 0.807
Block 3
rs10020464 rs2305948 rs7692791          
C C C     0.463 0.455 0.772
C C T     0.246 0.248 0.910
T C T     0.196 0.170 0.230
T T T     0.086 0.121 0.034
Block 4
rs2305949 rs6837735            
C C       0.614 0.623 0.735
T C       0.201 0.219 0.403
C T       0.185 0.158 0.187
Block 5
rs12502008 rs7667298 rs2239702          
T C G     0.357 0.356 0.953
G T A     0.255 0.249 0.789
G T G     0.217 0.198 0.394
G C G     0.171 0.198 0.199

Five haplotype blocks were identified for the tagging single nucleotide polymorphisms (tSNPs) in VEGFR-2 using Haploview. Haplotype frequencies in neovascular age-related macular degeneration patients (cases) and participants without age-related macular degeneration (controls) are reported with corresponding p-values. Haplotypes with frequencies above 0.01 are included in the table.

Fang, Mol Vis 2009; 15:2710-2719. http://www.molvis.org/molvis/v15/a287

©2009 Molecular Vision http://www.molvis.org/molvis/

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