Figure 2. Linkage disequilibrium map of VEGFR-2 tagging single nucleotide polymorphisms. Five haplotype blocks were identified for the 20 tagging single nucleotide polymorphisms (tSNPs) in the vascular endothelial growth factor receptor-2 (VEGFR-2) gene. A linkage disequilibrium map of these haplotype blocks was generated using Haploview. Length of each block is provided in kilobases (kb), and pairwise linkage disequilibrium (D’) is given for each SNP combination. Dark red shading denotes D’ values greater than 0.80, and empty squares indicate D’ values of 1.0.