Figure 3. Electroretinogram traces from a
laser-treated eye in a representative adult albino Swiss mouse.
Electroretinogram recordings in response to flash stimuli of increasing
intensity for the from a representative animal in group IV registered
before laser treatment (0 h) and 24 h, 1 week, 4 weeks, 6 weeks and 8
weeks later. We found a significant reduction in the scotopic threshold
response, a-wave, and b-wave amplitudes by 24 h after lasering,
amounting to approximately 81%, 64%, and 54% of their basal values,
respectively. The changes observed in the electroretinogram never fully
recovered for survival times of up to 8 weeks after lasering,
indicating that these are permanent.