Figure 4. Changes in miR-29b induced by chronic oxidative stress. To investigate if miR-29b changes with chronic oxidative stress, three human trabecular meshwork (HTM) cell lines were incubated during 4 days at 40% oxygen, and the changes in the expression of miR-29b were quantified by quantitative–PCR (Q-PCR) and compared to nonstressed controls incubated at 5% oxygen. The figures represent the logarithm of the fold change in gene expression between cells incubated at 40% oxygen compared to controls. Bars represent standard error from three different measurements. One asterisk means p≤0.05.