Table 2 of Kato, Mol Vis 2009; 15:2470-2474.

Table 2. Polymorphic changes identified in CYP1B1 in beagles.

Analysis of
canine samples		 Exon 2 5’-UTR
Mutational changes Genotype Polymorphic changes Genotype
1 normal P93P homozygote 109 A→C heterozygote
9 normal P93R heterozygote ND —
3 normal R93R homozygote ND —
3 affected P93R heterozygote 109 A→C heterozygote
2 affected R93R homozygote 109 A→C heterozygote
2 carriers P93R heterozygote 109 A→C heterozygote

The affected dogs have POAG. In the table, ND refers to not determined, P refers to proline (normal amino acid), and R refers to arginine.

Kato, Mol Vis 2009; 15:2470-2474. http://www.molvis.org/molvis/v15/a263

©2009 Molecular Vision http://www.molvis.org/molvis/

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