Table 5 of Chen, Mol Vis 2009; 15:2349-2357.


Table 5. The sensitivity, specificity, positive and negative predictive values for the risk alleles and genotypes of the three SNPs of LOXL1.

SNP SE (95%CI) SP (95%CI) PPV (95%CI) NPV (95%CI)
rs1048661
allele (T) 0.877(0.786-0.968) 0.198(0.128-0.268) 0.0022(0.0019-0.0025) 0.9988(0.9988-1.00)
genotype (TT) 0.823(0.717-0.929) 0.771(0.697-0.845) 0.0072(0.0047-0.0097) 0.9995(0.9992-0.9998)
rs3825942
allele (G) 0.948(0.886-1.00) 0.037(0.004-0.070) 0.0020(0.0019-0.0021) 0.9972(0.9930-1.00)
genotype (GG) 0.948(0.886-1.00) 0.206(0.135-0.277) 0.0024(0.0021-0.0027) 0.9995(0.9989-1.00)
rs2165241
allele (C) 0.948(0.886-1.00) 0.022(0.004-0.048) 0.0019(0.0017-0.0020) 0.9953(0.9875-1.00)
genotype (CC) 0.912(0.833-0.991) 0.213(0.141-0.285) 0.0023(0.0020-0.0026) 0.9992(0.9984-1.00)