Table 4 of Greiling, Mol Vis 2009; 15:2313-2325.

Table 4. Changes in non-crystallin proteins with age were determined in zebrafish lenses by shotgun proteomics analysis and selected abundant proteins are listed.


Protein		 Rank order (relative abundance)
Chromosome
IPI
4.5 days 3 weeks 6 weeks 6 months
Calpain 3 14 13 16 38 17 IPI00489320.1
Major intrinsic protein of lens fiber 1 49 63 96 31 23 IPI00485872.1
Major intrinsic protein of lens fiber 2 32 47 126 76 23 IPI00607319.3
Grifin - 34 36 42 3 IPI00506063.2
Lengsin - 57 38 30 11 IPI00486208.6
Scinla - 86 107 183 6 IPI00772565.3
Valosin-containing protein 20 33 34 44 5 IPI00505091.2
Thimet oligopeptidase 1 78 58 49 56 11 IPI00511724.1
β Actin 1 31 23 33 36 1 IPI00482295.2
Tubulin α2 36 56 99 - 11 IPI00488901.1
Tubulin β2B 54 69 - 232 5 IPI00494039.2
CP49/Bfsp2 - 79 25 17 2 IPI00512700.3
Vimentin - - 82 39 24 IPI00494222.1
Eukaryotic translation EF1-alpha 19 18 23 34 19 IPI00512240.1
Transketolase 35 35 - 141 23 IPI00498510.1
GAPDH - 31 77 58 16 IPI00487455.2
Histone H2A-like 55 22 46 75 25 IPI00486495.1

The numbers in columns 2–5 represent the rank order of protein abundance at each age listed (i.e., “1” indicates the most abundant protein detected in the lens). The top six rows list non-crystallin proteins with known functions in the zebrafish lens. The middle section lists five cytoskeletal proteins, and the last four rows list ubiquitous proteins. IPI refers to the International Protein Index reference number.

Greiling, Mol Vis 2009; 15:2313-2325. http://www.molvis.org/molvis/v15/a248

©2009 Molecular Vision http://www.molvis.org/molvis/

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